25 Mar New Research Low Carbohydrate Diet Helps Improve Antiviral Immune Function
In this study, we show that the consumption of a low-carbohydrate, high-fat ketogenic diet (KD) protects mice from lethal IAV infection and disease. KD feeding resulted in an expansion of γδ T cells in the lung that improved barrier functions, thereby enhancing antiviral resistance.
Expansion of these protective γδ T cells required metabolic adaptation to a ketogenic diet because neither feeding mice a high-fat, high-carbohydrate diet nor providing chemical ketone body substrate that bypasses hepatic ketogenesis protected against infection.
Therefore, KD-mediated immune-metabolic integration represents a viable avenue toward preventing or alleviating influenza disease.
The preliminary studies on mice who are feed a low carbohydrate diet provide exciting new evidence for improvement of immune function specifically antiviral in the lungs to help protect against viruses. More research is needed with human trails hopefully coming soon in the future. This appears to be another benefit for low carbohydrate diet in addition to blood sugar control, weight loss, and now possibly improved immune function.
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